Meruyert Alyonova, Raikhan Mustafina, Leila Sultanayeva, Galia Zamaratskaia, Yuriy Balji

Introduction

Bovine mastitis remains one of the most prevalent and economically important diseases in dairy farming, leading to reduced milk yield, lower milk quality, and higher treatment costs. This problem is particularly pronounced in parts of Central Asia, including Kazakhstan, where both clinical and subclinical forms occur at high levels in commercial herds. On dairy farms in East Kazakhstan, clinical mastitis affected up to 35% of cows in some years, with subclinical mastitis prevalence similarly high, indicating that the disease remains widespread despite ongoing prevention efforts (Mukhamadieva et al., 2023). The high incidence of udder inflammation in this region reflects broader challenges in feeding, housing, and herd management, making mastitis a persistent health and economic concern for local dairy farmers.

Recent research has emphasized the important role of the mammary gland microbiota in maintaining udder health and in the development of inflammatory disorders. Advances in next‑generation sequencing (NGS) techniques have enabled detailed profiling of microbial communities, including bacteria that cannot be cultured traditionally, providing new insights into the microbial dynamics underlying mastitis (Derakhshani et al., 2018). The present study aimed to investigate changes in the composition and structure of the mammary microbiota in dairy cows across healthy, subclinical, and clinical mastitis conditions.

This study was supported by the Ministry of Science and Higher Education of the Republic of Kazakhstan, project AP23484620, “Development and Implementation of Phytogenics and Phytobiotics for Prevention and Treatment of Mastitis in Animals with Assessment of Milk Quality and Safety”.

Full version of the article: 265. Dysbiosis of the udder microbiota.pdf

For citation: Meruyert Alyonova, Raikhan Mustafina, Leila Sultanayeva, Galia Zamaratskaia, Yuriy Balji. Dysbiosis of the udder microbiota as a risk factor for mastitis in cows. IDF Mastitis and Milking Technology Joint Conference 2026 Proceedings 10-13 March 2026. P.131-134.